The current research effort investigates whether experiencing a goal frustration increases a person’s willingness to endure harm as a means to an end (i.e. purposive harm endurance). All studies randomly assigned participants to experience a goal frustration in the form of an unexpected goal violation (e.g., unexpectedly failing a test) or to a control/comparison group. Three different manipulations, and three different measures, of purposive harm endurance provide support for the inclusion of purposive harm endurance in the family of outcomes associated with goal frustration or goal blockage. The first study revealed that a more intense goal frustration caused higher willingness to endure purposive harm than a less intense goal violation. The second study replicated the first and showed that increased demand for the goal mediated the relationship between experiencing a goal frustration and an increased willingness to endure purposive harm. The third study offered additional support for the impact of frustrations on purposive harm endurance and also revealed increases in purposive harm endurance do not occur in isolation. Reduced goal fluidity, reduced feelings of creativity, and increased feelings of aggression support the nomological validity of the proposed construct.